Wednesday, January 21, 2009

Stress Related Disorders Sourcebook or Shots in the Dark

Stress-Related Disorders Sourcebook

Author: Amy L Sutton

Nearly half of U.S. adults report concern about the stress in their lives, with work and money leading the list of major stressors. Stress is sometimes caused by traumatic events such as death, divorce, or mass disaster, but it often develops due to everyday frustrations with career, financial difficulties, technology, or caregiving. Stress impacts both physical and mental health by contributing to such problems as sleeplessness, reduced immunity, diabetes, depression, and anxiety. In severe cases, untreated or chronic stress may even lead to substance abuse, posttraumatic stress disorder, or suicide.

Stress-Related Disorders Sourcebook, Second Edition provides information about the origins and types of stress and describes physical and mental health disorders that may develop during and after stressful situations. Readers will learn about the link between stress and chronic pain, cardiovascular disease, and digestive disorders. The Sourcebook also discusses how stress contributes to mental health problems, including depression, anxiety disorders, posttraumatic stress disorder, and addition to tobacco, alcohol, and drugs. Information about trauma, loss, and grief is presented, along with comprehensive facts about stress management techniques, such as relaxation training, meditation, exercise, and anger management. Tips on helping children and teens cope with stress are also offered, along with a glossary of related terms and a directory of resources.

Savannah Schroll Guz Copyright 2007 Reed Business Information - School Library Journal

Divided into six thematic categories and 62 chapters, this excellent resource has been revised to include the field's newest data. American-centered statistics have been collected from nearly 20 government agencies to illustrate explanatory text. The issues explored include genetic predispositions to stress, exacerbating environmental factors, diverse physical consequences, and management techniques. Sutton (Fitness and Exercise Sourcebook) astutely incorporates a conceptual overview of stress and its promotion of illness. The book concludes with a ten-page list of federal and private-sector organizations supporting stress education. Although intended for professionals, it is accessible to the lay reader. Highly recommended for medical and psychiatric collections.

Look this: Legendary Illinois Cookbook or Real Fast Indian Food

Shots in the Dark: The Wayward Search for an AIDS Vaccine

Author: Jon Cohen

When scientists proved in 1984 that HIV causes AIDS, a vaccine race spun into action. But the race to develop an AIDS vaccine now more closely resembles a crawl. Jon Cohen elucidates the forces that have hindered the search: unforeseen scientific obstacles, clashing personalities, the uncertain marketplace, haphazard political organization, and serious ethical dilemmas. "Richly documented" (Washington Post). "Cohen's description of events is gripping, ... but his most valuable contribution is his prescription for advancing the effort to develop a vaccine" (Scientific American).

Robert Gallo

[A]n important book not only for the now but for the future of this epidemic and those to come.

Seth Berkley

Meticulously researched, cogently argued, and highly readable...the most important AIDS book since...And the Band Played On.

Barry R. Bloom

[Cohen's] intimate knowledge of the thinking and personalities of the major players,... uniquely captures the real drama of science.

Publishers Weekly

In 1984, overzealous scientists proclaimed they would develop an AIDS vaccine in a mere two years. Now, 16 years later, researchers are still battling the bureaucracy and each other to decide which potential vaccines should be tested and who should pay for the testing. Although Cohen, a veteran science writer (who presently writes for Talk magazine) originally intended to document one year of the vaccine search effort, he quickly realized that "one year doesn't mean anything to AIDS vaccine researchers." Because of a lack of leadership, organization, funding and urgency, it may take a year for some scientists just to raise enough funding to subsidize their work. As Cohen notes, many of the major pharmaceutical companies--frightened by the liabilities and low profit margins of vaccine research--have pulled out, leaving scientists to vie for limited government support. Unfortunately, the researchers controlling the federal purse strings, though distinguished, often harbor conventional views about how to approach vaccine research. Therefore, innovative approaches, such as engineering or deleting viral proteins and genes, are often disregarded as either too elaborate or too risky to warrant funding. The competition for grants promotes rivalry among scientists, a rivalry that Clinton hoped to quell when he announced his vision of a "Manhattan Project" for AIDS in 1992. Although the project never materialized, there has been a recent increase in federal funding for AIDS research that Cohen hopes will inspire the testing of promising vaccines. An insightful glimpse of a fractured but important process, this highly readable, thorough account may engage and spur AIDS activists and scientists to form a united front against a pervasive disease. 8 pages of photos not seen by PW. First serial to The Sciences; 5-city author tour. (Jan.) Copyright 2000 Cahners Business Information.

Library Journal

While popular fear and urgency has declined since the early years of the AIDS epidemic, the success of various treatments in improving the quality and duration of the lives of AIDS patients may only have lulled the public into a false sense of security. Already there is evidence that the virus has developed resistance to certain drugs, and in many parts of the world it still rages unchecked. Ten years ago, science reporter Cohen (Science and Talk magazines) began this book intending to document the story of the discovery of an AIDS cure. Today, his story is instead a chronicle of the failure to do so, owing to a combination of bad scientific research, haphazard leadership, and obstructive political and economic agendas. The author's exhaustive sources include scientific literature, company reports, and hundreds of personal interviews. Despite this book's harsh criticisms, Cohen's purpose is not to muckrake but to issue a wakeup call. This engaging story with a vital message is recommended for all libraries.--Gregg Sapp, SUNY at Albany Science Lib. Copyright 2001 Cahners Business Information.


Based on the complex technical, political, and ethical barriers to developing an AIDS vaccine which he chronicles, a California writer for magazine advocates a coordinated Manhattan Project- type effort by basic and applied researchers, business interests, and US government policymakers. Cohen concludes on the semi-hopeful note that, unlike the situation a decade ago, the world is now watching. Includes a glossary of medical terms. Annotation c. Book News, Inc., Portland, OR (

Talk Magazine

Cohen offers an accessible history of the now fractured state of AIDS research and the latest developments.

Scientific American - Nancy Padian

Jon Cohen brilliantly describes the inextricable weave of science, politics, legalities, ethics and business that, like a dysfuctional family, seems to have repelled the very cooperation that a successful vaccine effort needs most...Cohen's description of events is gripping, even whe he layus out the intricacies of molecular genetics, but his most valuable contribution is his prescription for advancing the effort to develop a vaccine.

What People Are Saying

Bill Gates
A wake-up call, a must-read for policy makers, scientific leaders and everyone who is working to stop AIDS.
—Bill Gates Sr., Co-Chair and CEO, Bill and Melinda Gates Foundation

Barry R. Bloom
This book reveals in a clear and powerful way the intellectual challenges AIDS vaccines pose for the scientific community.
—Barry R. Bloom, Dean, Harvard School of Public Health; Chairman of the UNAIDS Vaccine Advisory Committee

Robert Gallo
An important book not only for the now but for the future of this epidemic and those to come.
—Dr. Robert Gallo, professor and director, Institute of Human Virology, University of Maryland

Seth Berkley
This is the most important AIDS book since Randy Shilts sounded the alarm in And The Band Played On.
—Seth Berkley, M.D., President and Chief Executive Officer, The International AIDS Vaccine Initiative

Table of Contents:
Chapter 1Fast Predictions3
Chapter 2The Next Breakthrough16
Chapter 3Empiricists Versus Reductionists43
Chapter 4Moving into Humans64
Chapter 5Animal Illogic78
Chapter 6Market Forces102
Chapter 7Unwanted: Dead or Alive119
Chapter 8All MicroGeneSys's Men139
Chapter 9A Manhattan Project for AIDS175
Chapter 10The Dairymaids of AIDS200
Chapter 11Perpetual Uncertainty227
Chapter 12New World Order258
Chapter 13Running in Place295
Chapter 14Better Ways317
Chapter 15Disparate Measures333
Postscript: Breaking the Silence361

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